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FDA Approves Breakthrough Alopecia Drug, Cancer Vaccine Comes Closer

The FDA has approved a drug that has proven safe and effective for treating alopecia areata with an 80 percent success rate, while scientists say a vaccine for cancer is approaching.

FDA approves alopecia medicine, 80% effective in trials

On Monday, the Food and Drug Administration (FDA) approved the first rigid Emmett treatment for alopecia areata, an autoimmune disease that triggers sudden hair loss. Dermatology Times reported.

The drug is called baricitinib(brand name Olumiant), a once-daily pill developed by drugmaker Eli Lilly, NBC reported.

There were two trials of baricitinib in patients with at least 50% hair loss from the scalp measured by the severity of alopecia tool lasting more than 6 months.

In the first trial, 25% of patients receiving 4 milligrams of baricitinib, and 22% receiving 2 milligrams, achieved at least 80% of hair coverage at week 36 of treatment.

In the second trial, 32% who received 4 milligrams of baricitinib, and 17% who received 2 milligrams, achieved 80% of hair coverage at week 36 of treatment.

The most common side effects associated include upper respiratory tract infections, headaches, acne and high cholesterol.

Back in 2018, baricitinib was granted its original approval for the treatment of severely active rheumatoid arthritis, Fier Pharma reports. Recently, baricitinib was also approved as a new indication for treatment of SARS-Cov-2 in certain hospital admissions. Lilly has filed for alopecia indication by the end of 2021.

Scientists are getting closer to cancer vaccine

Scientists say they are getting closer to a vaccine that could be effective in triggering the immune system to identify and fight cancer cells.

While the development of the vaccine may still be years in the making, experts say the use of such vaccines will become standard practice as they become available, the Washington Post reported.

New approaches to vaccine development include those designed to differentiate tumor cells from normal cells with the aim of eliciting a response from the immune system against them. In addition, researchers are working on building immunotherapy drugs that increase the effectiveness of vaccines against cancer.

Many experts believe that our immune system is already undergoing a process known as “immuno-surveillance”, in which our bodies are constantly searching for cancers that are constantly trying to spring up and squeal.

“We have made so much progress in understanding how the immune system recognizes cancers,” said Vinod Balachandran, an oncologist and surgeon-scientist at the Memorial Sloan Kettering Cancer Center. “There are dozens of cancer vaccine candidates under study by researchers around the world.”

“Our bodies probably fight cancer all the time,” said Jay Berzofsky, head of the National Cancer Institute’s fax department. “The ones we discover and the ones that get into cancer that we have to treat are the ones that have escaped that immuno-surveillance. The tumors do it by learning how they can exploit the mechanisms that regulate the immune system. “

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FDA Approves Breakthrough Alopecia Drug, Cancer Vaccine Comes Closer

Source link FDA Approves Breakthrough Alopecia Drug, Cancer Vaccine Comes Closer

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